The ECS helps to support:

• Central Nervous System: Facilitates regeneration of neurons, synaptic plasticity, and neuroprotection. Regulates motor neuron activity and cognition.

• Digestive System: Regulates motility, gut-/brain-mediated food intake signaling, inflammation, gut permeability, and gut microbiome interactions.

• Hormones: Plays a significant role in the function of hypothalamic-peripheral endocrine axis for metabolic hormone release. Contributes to stress response by influencing hypothalamic-pituitary-adrenal axis.

• Bones: Plays an important role in bone homeostasis by maintenance of bone mass/density and bone resorption.

• Immune Response System: Supports healthy inflammatory response pathways.

• Metabolism: Constitutes a feedback loop for nutrientenergy metabolism. Regulates various cellular functions, intestinal functions, immune responses, and stress responses. Supports physiological homeostasis in the body as cannabinoids co-evolve with diet.

• Muscles: Improves muscle glucose uptake, mitochondrial energetics, and supports runner’s high