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Ventilator Management 101

MECHANICAL VENTILATOR MANAGEMENT: A PRACTICAL GUIDE

Mechanical ventilation is a life-saving intervention used in critically ill patients who are unable to maintain adequate oxygenation or ventilation on their own.


Effective ventilator management requires a solid understanding of respiratory physiology, ventilator modes, settings, and vigilant patient monitoring.


This blog provides a clear and practical overview of mechanical ventilator management, particularly useful for Respiratory therapist students, Nursing students, and healthcare professionals working in acute and critical care settings.


What is Mechanical Ventilation?

Mechanical ventilation is the use of a machine (ventilator) to assist or fully replace spontaneous breathing. It can be delivered invasively through an endotracheal tube or tracheostomy, or non-invasively via masks (e.g, BiPAP or CPAP)


Main goals of mechanical ventilation:

  • Maintain adequate oxygenation
  • Ensure effective ventilation (CO2 removal)
  • Reduce work of breathing
  • protect the lungs from further injury


Indications for Mechanical Ventilation

  • Apnea
  • Acute respiratory failure (hypoxemic or hypercapnic)
  • Severe pneumonia or ARDS
  • COPD exacerbation
  • Neuromuscular disorders (e.g., Guillain-Barre syndrome)
  • Decreased level of consciousness
  • Post-operative respiratory support


Ventilator Modes

1. Assist- Control (A/C)

  • Each breath is either patient-triggered or time-triggered
  • Commonly used mode of ventilation
  • The patient may initiate as many ventilator breaths as required above the set rate; therefore, the patient’s VE is not consistent


2. Synchronized Intermittent Mandatory Ventilation (SIMV)

  • Allows for spontaneous breathing along with positive pressure ventilator breaths. It senses when the patient is breathing spontaneously; therefore, no “breath stacking” occurs.
  • It is used as both a weaning technique and for ventilation before weaning


3. Pressure Support Ventilation (PSV)

  • This type of ventilation aids in the weaning process from the ventilator
  • It is a patient-triggered, pressure-limited, flow-cycled breath, which maybe augmented with SIMV or used by itself in the CPAP mode
  • It is used to make spontaneous breathing through the ET tube during weaning more comfortable by overcoming the high resistance and increasing inspiratory work caused by the ET tube ( 5 to 10 cm H2O is all that is required to overcome tubing resistance)
  • An inspiratory pressure is set (usually 5 to 10 cm H2O for weaning purposes). As the patient initiates inspiration, the preset pressure is reached and held constant until a specific inspiratory flow is reached. then the pressure is terminated.
  • The inspiratory pressure level may be set to achieve a specific VT


4. Continuous Positive Airway Pressure (CPAP)

  • May be achieved with the use of CPAP mask, nasal prongs, or intubation and a ventilator.
  • A preset pressure is maintained in the airways and alveoli as the patient breathes totally on his or her own. No positive pressure breaths are delivered.
  • Patients whose PaO2 level cannot be maintained within normal limits using a 50% to 60% or more O2 mask and who have normal or low PaCO2 levels should be placed on CPAP. CPAP is also indicated for patients with obstructive sleep apnea who gain benefit form the positive airway pressure, which relieves the obstruction in the upper airway
  • CPAP setups should always have a low-pressure alarm so that leaks in the system are detected

Ventilator Settings

1. Tidal Volume (VT)

  • usually set at 6-8 mL/kg of ideal body weight
  • Lower tidal volumes are used in ARDS to prevent lung injury


2. Respiratory Rate (RR)

  • Determines minute ventilation
  • adjusted based on PaCO2 levels


3. Fraction of Inspired Oxygen (FiO2)

  • Percentage of oxygen delivered to the patient
  • Aim to keep FiO2 lesser than or equal to 60% when possible to avoid oxygen toxicity


4. Positive End-Expiratory Pressure (PEEP)

  • Used to maintain positive pressure in the airway after a ventilator breath
  • Excessive PEEP levels may lead to decreases in PaO2 and lung compliance by over-distending already open alveoli and shunting blood to collapsed alveoli
OPTIMAL PEEP: The level of PEEP that improves lung compliance (CL) without cardiac compromise


a. Indications for PEEP

  • Atelectasis
  • PaO2 of lesser than 60 mmhg on FiO2 of greater than 50% O2
  • Decreased functional residual capacity
  • Decreased Lung compliance
  • Pulmonary edema


b. Hazards of PEEP

  • Barotrauma
  • Decrease venous return
  • Decreased cardiac output
  • Decreased urinary output


5. Inspiratory flow control

  • Normal setting: 40 to 80 L/min
  • Adjusting the flow rate alters the inspiratory time, therefore altering the I:E ratio


6. I:E ratio

  • A comparison of the inspiratory time with the expiratory time
  • Established by the use of three ventilator controls for volume controlles ventilation
Normal I:E ratio for the adults is 1:2
Normal I:E ratio for infants 1:1


7. Sensitivity Control

  • Determines the amount of patient effort required to trigger the ventilator into inspiration
  • Should be set to the patient generates 0.5 to 2.0 cmH2O pressure. This is referred to as pressure triggering

Trigger Variable

1. Control: Time-Triggered

  • Initiation of the mechanical breath based on the set time interval for one complete respiratory cycle (inspiratory time and expiratory time)


2. Pressure-Triggered

  • Initiation of a mechanical breath on the drop in airway pressure that occurs at the beginning of a spontaneous inspiratory effort


3. Flow-Triggered

  • Flow-triggering strategy uses a combination of continuous flow and demand flow. Before inspiration, the delivered flow equals the return flow. As the patient initiates a breath, the return flow to the ventilator is decreased and this flow differential triggers a mechanical breath.

Patient Assessment and Monitoring


Key Assessments:

  • Vital signs and oxygen saturation
  • Chest inspection and breath sound
  • Fluid balance and anion gap
  • Transcutaneous blood gas monitoring
  • Arterial blood gases (ABGs)
  • Ventilator alarms and waveforms
  • Level of consciousness and comfort


Complications of Mechanical Ventilation

  • Barotrauma- resulting from excessive airway pressure (resulting from excessive airway pressure)
  • Pulmonary Infection
  • Atelectasis
  • Pulmonary Oxygen toxicity
  • Tracheal Damage
  • Decrease venous return to the heart
  • Decreased Urinary output
  • Lack of nutrition

Ventilator Alarms and Monitoring

1. Low-Pressure Alarm

  • Should be set 5-10 cm H2O below PIP
  • Activated by leaks in the ventilator circuit, leaks around the chest tube, a ruptured ET tube cuff, inadequate cuff pressure, or patient disconnection


2. High-Pressure Alarm

  • Should be set about 10 cm H2O above PIP
  • When the high-pressure limit is reached with volume-controlled ventilation, inspiration ends prematurely, decreasing delivered VT
  • Activated by: Decreasing Lung Compliance (CL) and Increasing airway resistance (RAW)


3. Low PEEP/CPAP Alarm

  • Should be set 2 to 4 cm H2O below the baseline level
  • This alarm is activated same reason with Low pressure alarm


4. Apnea Alarm

  • Maximum accepted level is 20 seconds or may be set so the patient will not miss more than two consecutive breaths
  • This alarm is activated after a set time passes with no inspiratory flow through the tubing
  • Important alarm for patients on CPAP mode, pressure support ventilation (PSV), or with low SIMV rates


5. Low Tidal Volume (VT) Alarm

  • Should be set approximately 10% below the set VT
  • Activated same reason with low-pressure alarm


6. Mean Airway pressure or MAP (Paw) Monitoring

  • Paw is the average pressure applied to the airway over a specific time
  • Directly affected by: Ventilator rate; PIP; PEEP level; pressure waveform; I:E ratio


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