Description

This Master Prompt focuses on the stage of Design of Experiments where the research objective progresses beyond factor screening toward detailed modeling of curvature, nonlinear factor–response relationships, interaction structures, prediction, operating-region identification and experimental optimization. Response Surface Methodology (RSM) forms the central framework, incorporating Central Composite Design (CCD), Box–Behnken Design (BBD), Doehlert Design and related second-order experimental designs.