The Missense Map | Kitson Maxxing Learning, Book 10 (Maxxing Edition)

Ziga Avsec, the Google DeepMind team behind AlphaMissense, and seventy-one million possible changes in our proteins

The full story of AlphaMissense from the Google DeepMind team, with Ziga Avsec as its last-listed author: the variant interpretation problem, the team, how population data became training labels, the catalogue of 71 million scored variants and its licence, every key figure attributed, independent evaluations both positive and negative, and a full chapter on limits. A research tool, not medical advice.

Inside:

• The method, explained properly
• Every figure sourced and dated
• Not a diagnosis: the limits
• Timeline, glossary and key papers annotated

The Maxxing Edition: a 53-page professional non-fiction ebook (PDF, 6x9 paperback style) from Kitson Workshop, with a foreword, a dated timeline, a glossary, key papers annotated, and full sources and notes. Companion to Kitson Maxxing Learning, episode 10, on YouTube. Free sample available: the foreword and chapter one.

Independent: written from published papers and institutional sources; not endorsed by the people or organisations named. For educational purposes only; not medical, financial or professional advice.