Obesogenic: The Quiet Biology Driving Black Obesity In A World Engineered To Make Everyone Sick

What if your body isn't resisting insulin? What if it's simply making too much of it?

That single distinction is at the heart of Obesogenic. Dr. Adaure Osuji, a UK-trained GP now based in Australia, introduces the Glucose Hyper-Responder (GHR) phenotype: a pattern of insulin hypersecretion and poor clearance that hides in plain sight, separate from the insulin resistance most people have heard of - and largely unrecognised by the worldwide medical establishment.

It may also help explain something many people on GLP-1 medications have quietly wondered: why the same drug works so differently from person to person. If your insulin pattern isn't what your doctor assumes it is, your response to treatment might not be either.

Osuji traces this hidden thread through a surprising list of conditions - PMOS (formerly PCOS), pregnancy-related complications, tinnitus, Menière's disease, and some types of cancer among them - and shows how a diagnostic blind spot in standard HbA1c testing has left this pattern especially underrecognised in people of African ancestry.

Written by a practising GP with over a decade of clinical experience, Obesogenic is a work of medical science and personal memoir - not a prescriptive guide or treatment manual. It does not tell you what medication to take or how to take it. It gives you something more valuable: a framework for finally understanding your own body's biology, and the language to advocate for the care you deserve.