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The Radium Girls - A Radioactive Case File

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Turn your introduction to radioactivity into a historical investigation!

Step into the 1920s and investigate the mysterious illnesses affecting young women who worked painting glow-in-the-dark watch dials. In this interactive, evidence-based chemistry activity, students become investigators tasked with uncovering what happened to the Radium Girls.

Students will examine historical-style advertisements, factory procedures, worker medical records, and chemistry evidence to piece together the case. As they progress through the investigation, they will connect the properties of radium to its effects on the human body and discover why a substance once marketed as a miracle could have devastating consequences.

Rather than simply reading about radioactive decay, students explore the human story behind the science and develop questions that lead naturally into your radioactivity unit.


๐Ÿ”Ž What's Included?

  • Case File 1: A Promising Job

Examine a 1920s-style hiring advertisement and consider why the position appealed to women.

  • Case File 2: The Miracle Element

Investigate historical advertisements for radium-containing products and explore how radium was marketed to the public.

  • Case File 3: A Day at the Factory

Learn about the dial-painting process, worker routines, and potential routes of radioactive exposure.

  • Case File 4: Something Is Wrong

Analyze five worker medical records to identify patterns in symptoms and develop a scientific hypothesis.

  • Case File 5: The Chemistry Clue

Compare calcium and radium on the periodic table and investigate why radium can accumulate in bones and damage surrounding tissue.

  • The Final Case Report

Use evidence from the investigation to explain what happened to the Radium Girls, evaluate the dangers of internal radioactive exposure, and develop new scientific questions.


๐Ÿงช Chemistry Concepts

This activity introduces students to:

  • Radioactivity and radioactive materials
  • The periodic table and chemical families
  • Similarities between calcium and radium
  • Biological effects of radiation
  • Internal radioactive exposure
  • Evidence-based scientific reasoning


Give your students a mystery to solve, evidence to investigate, and a scientific discovery to make.

The Radium Girls: A Radioactivity Case File is an engaging way to introduce the dangers of radioactive materials while helping students understand the chemistry behind a real historical tragedy.

You will get a PDF (23MB) file