Intro to Cannabinoids: CBD, CBG, THC and CBN. A Clinician Primer (Nationwide Edition, PDF)

Your patients are hearing about CBG for focus and CBN for sleep. This 9-page primer helps you separate what is studied from what is marketed. Every claim is tied to a source you can check.

Inside:

- A one-page at-a-glance table comparing THC, CBD, CBG and CBN

- What each cannabinoid is and its mechanism basics (receptors, metabolism)

- Honest evidence strength: National Academies (2017) conclusions quoted word for word, recent Cochrane reviews, and a plain statement that CBG and CBN evidence is limited and mostly preclinical

- Known adverse effects from FDA labels and PubMed-indexed trials and reviews

- Interaction considerations to review with a pharmacist, such as CBD and CYP enzymes, cited with no verdicts

- FDA-approved cannabinoid drugs (Epidiolex, dronabinol, nabilone) from their FDA labels

- Federal status as of October 2026 from the Federal Register, plus a "State rules vary" note that points to NCSL

- A clickable contents page and 34 numbered, tagged sources

The same clean clinician format as the Top 10 Conditions pack. No doses, no product picks, no hype.

Education only. This primer is a research-navigation aid. It is not medical, legal or prescribing advice. It does not diagnose, prescribe, recommend products, set doses or titration, or give drug-interaction verdicts. Findings are summarized for orientation only. Read the original sources before relying on any of them. Clinical decisions remain with the treating clinician. Confirm all laws and program rules on official state sites. For use with licensed, state-regulated medical cannabis programs and FDA-approved drugs only.

Sources include the National Academies of Sciences, Engineering, and Medicine (2017), Cochrane reviews, studies indexed in PubMed, NIH pages (NCCIH and others), FDA drug labels and agency pages, the Federal Register, and the National Conference of State Legislatures (NCSL). This is an independent guide and is not endorsed by any cited source. Prepared by Annie Romelfanger, author of Medical Cannabis Handbook: A Friendly Guide to Safe, Simple Healing. Last reviewed: October 2026. Corrections: romelfanger@proton.me.