CANCER AND INFLAMMATION MECHANISMS

• CONTENTS

CONTRIBUTORS ix

PREFACE xv

SECTION I GENERAL OVERVIEW OF
INFLAMMATION-RELATED CANCER

CHAPTER 1 INFECTION, INFLAMMATION, AND CANCER: OVERVIEW 1
Hiroshi Ohshima, Noriyuki Miyoshi, and Susumu Tomono

CHAPTER 2 STEM CELL THEORY AND INFLAMMATION-RELATED CANCER 9
Toshihiko Tanno and William Matsui

CHAPTER 3 EPITHELIAL–MESENCHYMAL TRANSITION: A LINK BETWEEN
CANCER AND INFLAMMATION 23
Jonas Fuxe and Mikael C. I. Karlsson
SECTION II BIOCHEMISTRY IN INFLAMMATION-RELATED
CANCER

CHAPTER 4 ROLE OF NITRATIVE DNA DAMAGE IN INFLAMMATIONRELATED
CARCINOGENESIS 41
Yusuke Hiraku and Shosuke Kawanishi

CHAPTER 5 LIPID PEROXIDATION–DERIVED DNA ADDUCTS AND THE
ROLE IN INFLAMMATION-RELATED CARCINOGENESIS 61
Helmut Bartsch and Urmila Jagadeesan Nair

CHAPTER 6 LEVEL OF INFLAMMATION-RELATED DNA ADDUCTS IN
HUMAN TISSUES 75
Tomonari Matsuda, Pei-Hsin Chou, and Haruhiko Sugimura
v

vi CONTENTS

SECTION III MOLECULAR BIOLOGY IN
INFLAMMATION-RELATED CANCER
CHAPTER 7 TOLL-LIKE RECEPTORS: ROLE IN INFLAMMATION AND
CANCER 83
Sarang Tartey and Osamu Takeuchi
CHAPTER 8 INFLAMMASOMES AND INFLAMMATION 103
Kaiwen W. Chen, Ayanthi A. Richards, Alina Zamoshnikova,
and Kate Schroder

CHAPTER 9 ACTIVATION-INDUCED CYTIDINE DEAMINASE: AN INTRINSIC
GENOME MODULATOR IN INFLAMMATION-ASSOCIATED
CANCER DEVELOPMENT 119
Hiroyuki Marusawa and Tsutomu Chiba

CHAPTER 10 MicroRNA AND INFLAMMATION-RELATED CANCER 131
Zhaojian Gong, Zhaoyang Zeng, Pranab Behari Mazumder, Jian Ma,
Ming Zhou, Xiayu Li, Xiaoling Li, Wei Xiong, Yong Li, and Guiyuan Li

CHAPTER 11 INFLAMMATION AS A NICHE FOR TUMOR PROGRESSION 149
Futoshi Okada
SECTION IV INFLAMMATION-RELATED CANCER INDUCED BY
SPECIFIC CAUSES

CHAPTER 12 HUMAN PAPILLOMAVIRUS AND CERVICAL CANCER 165
Kurt J. Sales

CHAPTER 13 HEPATITIS VIRUSES AND HEPATOCELLULAR CARCINOMA 181
Wai-Kay Seto, Ching-Lung Lai, and Man-Fung Yuen

CHAPTER 14 EPSTEIN–BARR VIRUS AND NASOPHARYNGEAL CARCINOMA 193
Xiaoying Zhou, Xue Xiao, Fu Chen, Tingting Huang, and Zhe Zhang

CHAPTER 15 BARRETT’S ESOPHAGUS AND ESOPHAGEAL CANCER 213
Albert Roessner and Angela Poehlmann
CONTENTS vii

CHAPTER 16 ASBESTOS-INDUCED CHRONIC INFLAMMATION AND CANCER 223
Andrea Napolitano, Sandro Jube, Giovanni Gaudino, Harvey I. Pass,
Michele Carbone, and Haining Yang

CHAPTER 17 NANOMATERIALS 235
Yiqun Mo, Rong Wan, David J. Tollerud, and Qunwei Zhang

CHAPTER 18 INFLAMMATORY PATHWAYS OF RADIATION-INDUCED
TISSUE INJURY 249
Danae A. Laskaratou, Iigeneia V. Mavragani, and
Alexandros G. Georgakilas

CHAPTER 19 PHOTOCARCINOGENESIS AND INFLAMMATION 271
Chikako Nishigori
SECTION V. PREVENTION OF INFLAMMATION-RELATED
CARCINOGENESIS

CHAPTER 20 CHEMOPREVENTION OF COLORECTAL CANCER BY
ANTI-INFLAMMATORY AGENTS 285
Michihiro Mutoh, Mami Takahashi, and Keiji Wakabayashi

CHAPTER 21 NUTRACEUTICALS AND COLON CANCER PREVENTION 301
Deepak Poudyal and Lorne J. Hofseth

CHAPTER 22 CANCER CHEMOPREVENTION BY TARGETING COX-2 USING
DIETARY PHYTOCHEMICALS 339
Kyung-Soo Chun and Young-Joon Surh

CHAPTER 23 REGULATION OF INFLAMMATION-ASSOCIATED INTESTINAL
DISEASES WITH PHYTOCHEMICALS 355
Akira Murakami