Imperfect by Lauren Shiro

Carol Mathers: born a sickly child, in a home fraught with undercurrents that threaten to sweep away any chance she might have for a normal life. Now in her mid-thirties, she's a highly sought-after IT guru in St. Louis. She has built a great life for herself with her partner, Alexandria, even though the two face prejudice as lesbians, and as an interracial couple -fighting tragedy and sometimes, finding triumph. 

During her tumultuous life, Carol discovers that she has acquired AIDS as a result of a childhood transfusion from the dark period of time before AIDS was widely known... or understood, not even by the medical profession. Now, the two women face even more obstacles, prejudice, and a strange, new life as AIDS patients. Carol learns just how much her chaotic past has affected her, and how she can never really escape it, even as she tries to move on with her life. 

An unexpected event creates even more pain and tragedy in Carol's life, and causes her to wonder about the meaning of and purpose of her own life... or if there is any purpose at all...