Phosphatase Screening

Protein phosphorylation is vital for normal cellular function and a major control mechanism of a wide range of physiological processes. Phosphate groups are post-translational modifications that regulate many disease states, including cancers, neurological diseases, diabetes, pain, autoimmune disorders, and cardiovascular diseases. Actually, protein phosphorylation-mediated signaling events offer plenty therapeutic targets, and drug discovery efforts to date have brought over two dozen kinase inhibitors to the clinic.

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