Protein Interaction Introduction

A variety of specific macromolecular interactions such as protein-DNA, protein-RNA, protein-protein, protein-lipid and protein-carbohydrate interactions are important in biological systems. Since the specific interactions between the cellular macromolecules form the basis for all biological processes, the ability to manipulate the formation of these complexes will open up possibilities to selectively interfere with these processes. Understanding the physical basis for specificity in the different systems and mapping the various networks of interactions is central to the subsequent reengineering of the processes.