I am Danny LeVan-Cicchetti, an Italian mycologist and toxicologist dedicated to the study of the genus Amanita and the fascinating world of amatoxins. My work sits at the intersection of classical taxonomy, molecular phylogeny, toxicology, and the emerging therapeutic potential of fungal toxins in precision medicine.

I earned my Master’s degree in Natural Sciences from Sapienza University of Rome (cum laude), with a thesis focused on amatoxins toxicology. Since then, I have specialized in the systematics of Amanita section Phalloideae, the group that contains all known deadly poisonous Amanita species, commonly known as death caps and destroying angels. My research explores the evolutionary relationships within this section, variation in amatoxin production across lineages, and the morphological and phylogenetic characters that define these fungi.

As a scientific illustrator, I create detailed mycological artwork (particularly of Amanita species) that supports both research and education. I am active in the global mycology community as an administrator and contributor in specialist groups such as Amanita International, where I assist with identifications, share taxonomic updates, and create educational resources including high-resolution posters on Amanita sections and infographics on spore identification and section characteristics.

In May 2026 I published the open editorial “Amatoxins Against Cancer” (Tumori Journals). Drawing on my background as an amanitologist, the paper reviews the rapid advances (2024–2026) in using α-amanitin as a payload in antibody-drug conjugates (ATACs/ADCs). It highlights how these amatoxin-based therapies can overcome multi-drug resistance, target quiescent cancer stem cells, and show promise against both hematological malignancies and solid tumors, while discussing ongoing efforts (including work connected with Heidelberg Pharma) to optimize efficacy and minimize off-target hepatotoxicity. The piece emphasizes open dissemination to foster broader collaboration in this promising area of precision oncology.

Looking ahead, I am preparing a manuscript (expected 2026) that formally describes and names two new destroying angel species within Amanita section Phalloideae. This work continues my long-standing focus on clarifying the diversity and evolutionary history of the most toxic members of the genus.

My approach to mycology is deeply interdisciplinary: I combine rigorous taxonomic work with scientific illustration, community education, and translational research that connects fundamental fungal biology to real-world applications in medicine. Whether I am examining herbarium specimens, illustrating delicate veil remnants, or following the latest developments in amatoxin-based cancer therapeutics, my goal remains the same: to deepen our understanding of these remarkable organisms and contribute to both scientific knowledge and practical benefit.