New: HPLC, LC-MS and GC-MS Video Courses

Animated, narrated lessons that teach chromatography the way it is actually done in the lab. Each course comes with a companion book, a capstone case study and a final exam.

HPLC Course · 10 modules, 64 lessons, about 3 hours

LC-MS Course · 10 modules, 50 lessons, about 2 hours

GC-MS Course · 9 modules, 44 lessons, about 1.5 hours

Buy it once and it is yours to keep. Watch a free lesson on each course page, or get all three together in The Complete Chromatography Set.

See the Courses

About Me

From the Pharmaceutical Laboratory to Practical Tools

I'm Mirela Gorjanu, MSc, a pharmaceutical analytical scientist with more than 20 years in HPLC, LC-MS, method development, method validation and troubleshooting.

Knowing the science is only half the job. Knowing what to do when the experiment doesn't behave is the other half. Every guide, template and app here is built for that second half: the tailing peak, the lost resolution, the validation result that doesn't make sense, the method that fails after transfer.

Built for analysts in pharmaceutical R&D, QC, validation, stability, CROs and academia. Acceptance criteria are anchored to ICH Q2(R2), ICH M10 and USP.

New here? Start with the FREE HPLC / LC-MS Interview Survival Guide: payhip.com/b/dJPOb

Mirela Gorjanu · Founder, Practical Pharma Science™

Expand Your Learning

YouTube Channel: Watch step-by-step educational videos at YouTube/@PracticalPharmaScience.

Practical Pharma Science Website: Visit practicalpharmascience.com to access 20+ FREE practical HPLC & LC-MS tools. Plus, check out the Chromie Academy web application for free interactive courses!

pKa, LogP, LogD, LogS and pH: the "Fab Five" physicochemical properties that predict retention, peak shape and solubility before you ever inject a sample. You'll see why mobile-phase pH should sit about 2 units away from the pKa, why LogD (not LogP) predicts reversed-phase retention for ionisable drugs, and why LogS decides your diluent.

Applied Chromatographic Intelligence

Smarter HPLC Method Development

Expand Your Learning:

YouTube Channel: Watch step-by-step educational videos at YouTube/@PracticalPharmaScience.
Practical Pharma Science Website: Visit practicalpharmascience.com to access 20+ FREE practical HPLC & LC-MS tools. Plus, check out the Chromie Academy web application for free interactive courses!

PRACTICAL PHARMA SCIENCE™

Practical AI Tools & Training for Analytical Scientists

Practical Pharma Science™ brings together practical analytical-science software, visual training resources, practical guides, troubleshooting systems and laboratory-focused workflows created for scientists working with HPLC, LCMS, GCMS, method development, validation, DoE and pharmaceutical analysis.

WHY PRACTICAL PHARMA SCIENCE™?

REAL-WORLD EXPERIENCE

Created by Mirela Gorjanu, MSc, a pharmaceutical analytical scientist with more than 20 years of industry experience.

PRACTICAL FIRST

The goal is not to make analytical science more complicated.

The goal is to make it easier to understand, apply and teach.

VISUAL LEARNING

Complex concepts are transformed into structured workflows, diagrams, posters, practical examples and decision-based learning resources.

SCIENCE + TECHNOLOGY

Practical Pharma Science™ combines pharmaceutical analytical chemistry with modern AI-assisted tools and digital learning.

THE PRACTICAL PHARMA SCIENCE™ ANALYTICAL TOOLKIT

HPLC ASSIST PRO™

A practical AI-assisted workspace for HPLC method development, chromatographic optimisation and troubleshooting.

Explore method conditions, analyse chromatographic behaviour, investigate problems and structure your development workflow.

DoE ASSIST PRO™

Turn experimental design into a structured analytical workflow.

Work with factorial designs, response surface methodology, screening strategies, ANOVA, response surfaces, multi-response optimisation and design-space thinking.

METHOD VALIDATION ASSIST PRO™

A practical workspace for analytical method validation.

Structure your thinking around specificity, accuracy, precision, linearity, range, LOD/LOQ, robustness, solution stability, carryover, system suitability and related validation considerations.

Designed around the principles of modern analytical procedure development and validation.

DEGRADATION PATHWAY PLANNER PRO™

Build a more structured approach to forced degradation studies.

Explore stress conditions, degradation susceptibility, potential degradation pathways, structural alerts, controls and evaluation strategies.

CHROMATWIN™

A practical method-transfer workflow designed to help scientists understand gradient-delay and dwell-volume differences when transferring chromatographic methods between systems.

PRACTICAL TRAINING FOR ANALYTICAL SCIENTISTS

The software is only one part of Practical Pharma Science™.

The library also includes practical guides, visual reference resources, troubleshooting workbooks, method-development resources, validation templates, courses and interactive chromatography simulators.

HPLC METHOD DEVELOPMENT

Step-by-step practical resources for developing, understanding and improving chromatographic methods.

HPLC TROUBLESHOOTING

Diagnose common chromatographic problems through structured troubleshooting workflows and real laboratory scenarios.

METHOD VALIDATION

Practical resources covering analytical procedure validation, validation characteristics, documentation and calculation strategies.

LCMS & BIOANALYTICAL SCIENCE

Practical resources for LCMS method development, bioanalytical assays, validation and troubleshooting.

INTERACTIVE SIMULATORS

Explore chromatographic concepts interactively rather than learning only from static theory.

FEATURED RESOURCE

THE COMPLETE HPLC PRACTICAL PHARMA LIBRARY

A large practical collection of HPLC guides, troubleshooting resources, method-development references, validation materials and visual learning resources.

One collection. Multiple practical applications.

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Contact Us

Have a Question? Let's Talk.

Whether you have a question about a Practical Pharma Science™ product, need help choosing the right resource, or simply want to share an idea for a future analytical tool, we would love to hear from you.

Practical Pharma Science™ is built around real laboratory problems, so your questions and feedback are genuinely valuable.

Buying for a lab or company?

Paying by card or PayPal: after checkout, click Generate in your Payhip email receipt to download a PDF invoice with your company name, address and VAT/tax number.

Need an invoice before you pay (purchase order or bank transfer), or licences for several analysts? Email practicalpharma.science@yahoo.com with your company name, billing contact and number of users. You'll receive a quote and an invoice made out to your company, quoting your PO number.

IMPORTANT

Practical Pharma Science™ resources are designed for education, scientific workflow support and professional development. They do not replace laboratory procedures, validated methods, quality systems, scientific judgment, regulatory requirements or your organization's SOPs.

Mirela Gorjanu, MSc

Founder - Practical Pharma Science™

Practical Pharma Science™